The AHA announces the finalists for the 2021 Early Career Investigator Award


Evangelos (Evan) Oikonomou, MD, DPhil, was shortlisted for the Robert Levy Memorial Lecture and Lifestyle and Cardiometabolic Health Early Career Investigator Award competition. Oikonomou is a member of the section of cardiovascular medicine, a member of the ABIM Physician-Scientist Research Pathway program at the Yale School of Medicine, and the Cardiovascular Data Science Laboratory (CarDS).

In a project led by Oikonomou and Rohan Khera, MD, MS, The CarDS Lab recently developed a novel approach to constructing clinical trial computer phenomaps to characterize patient-level heterogeneity in the efficacy of therapies and medical interventions. This method has already made it possible to develop a new digital decision support tool for physicians called ASSIST, which aims to standardize the selection of the most appropriate test for the diagnosis of coronary heart disease (CAD).

Building on this work, the team has now extended the application of this method to landmark trials exploring the benefits of intensive reduction over standard blood pressure reduction. Oikonomou will discuss the full results of the study in the summary, “Individualize the Cardiovascular Benefits of Intensive Blood Pressure Reduction Using Computational Phenomaps from the SPRINT and ACCORD Trials” which will be presented on November 14, 2021 during the scientific sessions of the American Heart Association (AHA).

Sponsored by the Council on Lifestyle and Cardiometabolic Health, the Early Career Investigator Award in Lifestyle and Cardiometabolic Health honors the memory of Robert I. Levy, MD ’61, who led the first clinical trials that established the link between lowering blood pressure and prevention of coronary artery disease.

For more late-breaking research on Khera and Oikonomou during the 2021 science session, please visit

Submitted by Elisabeth Reitman on August 20, 2021

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